Treatment-Resistant Depression (TRD)

Treatment-resistant depression (TRD) occurs when one has been treated for depression but their symptoms haven’t improved.


  • Extended periods of sadness
  • Lack of happiness
  • Hopelessness
  • Drastic weight changes when not dieting
  • Erratic sleep patterns
  • Reduced self-confidence
  • Difficult concentrating
  • Lack of energy
  • Suicide ideation
  • Excessive guilt

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